History of Peyronie’s Disease

Peyronie’s Disease is an illness that is defined by the abnormal curvature of the penis during an erection. The disease was first described by the French surgeon François de la Peyronie in 1743. Since then, it has been a subject of interest for many physicians and researchers. The disease has been known by different names throughout history, and its etiology and treatment have been subject to much debate. In this article, we will provide a historical overview of PD for men, its clinical features, and the different treatments that have been used over time.

Historical Overview:

The first recorded description of Peyronie’s disease was in 1743 by the French surgeon François de la Peyronie, who gave it the name “La Maladie de La Peyronie”. Peyronie’s disease is also known as induratio penis plastica, fibrous cavernositis, penile induration, and chronic inflammation of the tunica albuginea. Peyronie’s disease is a connective tissue disorder that affects the tunica albuginea, which is the fibrous layer that surrounds the corpora cavernosa of the penis. The disease is characterized by the formation of fibrous plaques in the tunica albuginea, which results in the abnormal curvature of the penis during an erection.

The clinical features of Peyronie’s disease were well documented by John Hunter in the late 18th century. Hunter described the plaques as “hard, inelastic, cartilaginous-like lumps” that were located in the tunica albuginea. He also noted that the disease was more common in older men and that it could be associated with a history of trauma to the penis. However, what causes PD in men remained unclear until the 20th century.

In the 20th century, several theories were proposed to explain the etiology of Peyronie’s disease. In the early 1900s, it was thought that the disease was caused by inflammation of the tunica albuginea due to a bacterial infection. However, this theory was later disproven, and it is now known that Peyronie’s disease is not caused by an infection. In the mid-20th century, it was proposed that the disease was caused by a genetic predisposition, but this theory was also not conclusive. Currently, the most widely accepted theory is that Peyronie’s disease is caused by repetitive trauma or microtrauma to the penis.

Clinical Features:

Peyronie’s disease is characterized by the formation of fibrous plaques in the tunica albuginea, which results in the abnormal curvature of the penis during an erection. The plaques can be located anywhere along the shaft of the penis, but they are most commonly found on the dorsal side of the penis. The plaques are typically hard and inelastic, and they can cause pain during an erection. In addition to the curvature of the penis, Peyronie’s disease can also cause erectile dysfunction and a decrease in the size of the penis. Recent studies have shown that, Peyronie’s disease and Erectile Dysfunction are interlinked.

The severity of Peyronie’s disease can vary widely among individuals. In some cases, the curvature of the penis may be mild and not cause any significant problems. In other cases, the curvature may be severe and result in difficulty with sexual intercourse or painful erections. The disease can also have a significant impact on a man’s psychological well-being, leading to depression and anxiety.

Treatment:

Peyronie’s disease treatments has been subject to much debate over time. In the past, surgical intervention was the only treatment option available, and it was associated with a high risk of complications. However, in recent years, non-surgical treatments have become more widely available and have been shown to be effective in many cases.

Surgical Treatment

In the early days, Peyronie’s disease surgery involved the excision of the plaque or the release of the fibrous tissue causing the curvature. However, this approach was associated with a high risk of complications, such as erectile dysfunction and further curvature of the penis. In the mid-20th century, a new surgical technique called Nesbit’s procedure was developed. This procedure involved the excision of a segment of the tunica albuginea opposite to the plaque, which resulted in straightening of the penis. However, this approach also had a high risk of complications, including erectile dysfunction and shortening of the penis.

Non-surgical Treatment:

In recent years, non-surgical treatments have become more widely available and have been shown to be effective in many cases. The most common non-surgical treatments for Peyronie’s disease include oral medications, injection therapies, penile traction devices, shockwave therapy, EMTT therapy and NanoVi.

Oral Medications:

Oral therapies for Peyronie’s disease that are commonly used include vitamin E, potassium aminobenzoate, colchicine, and tamoxifen. These medications are thought to work by reducing inflammation and decreasing the production of collagen, which is the protein that forms the fibrous plaques. However, the effectiveness of these medications is still the subject of much debate, and their long-term safety has not been established.

Injection Therapies:

Injection therapies that are commonly used for the treatment of Peyronie’s disease include verapamil, interferon-alpha, and collagenase. Verapamil and interferon-alpha are thought to work by reducing inflammation, while collagenase is an enzyme that breaks down the fibrous tissue causing the curvature. Injection therapy is usually performed in an outpatient setting, and it is generally well-tolerated. However, the effectiveness of injection therapy varies widely among individuals, and it may not be suitable for all patients.

Penile Traction Devices:

Penile traction devices are another non-surgical treatment option for Peyronie’s disease. These devices apply a constant and gentle stretching force to the penis, which is thought to help break down the fibrous tissue causing the curvature. Penile traction devices are usually worn for several hours per day, and they can be used in combination with other non-surgical treatments, such as oral medications or injection therapy. The effectiveness of penile traction devices has been demonstrated in several clinical studies, and they are generally well-tolerated.

Shockwave therapy

Shockwave therapy for peyronie’s disease uses high-intensity acoustic waves to dissolve scar tissue and encourage the development of new blood vessels. This therapy is an innovative treatment option for PD. Many people find the process to be appealing because it is non-invasive and can often be executed in an outpatient environment. A device that generates low-intensity shockwaves to the penis is often used to administer shockwave therapy. The process is painless and takes 20 to 30 minutes from start to finish. In clinical studies, shockwave therapy for Peyronie’s disease has been proven to be successful. According to a research article published in the Journal of Sexual Medicine, shockwave therapy reduced discomfort and improved penile curvature in men with PD. Another research in the Journal of Endourology reported that shockwave therapy helped those with Peyronie’s Disease have better erectile function and penile curvature.

EMTT therapy

Extracorporeal magnetotransduction therapy, a procedure that is non-invasive and often known as EMTT therapy, was constructed specifically to treat musculoskeletal pain and other conditions. It has been proven to significantly improve men’s sexual health issues, including PD, when used in conjunction with other technologies like shockwave treatment, Tesla Chair, and NanoVi. The tiny cell level is where electromagnetic transduction therapy conducts itself. The endothelial cells found inside the millions of blood arteries of the penis get exposed to a strong magnetic field. These cells help the body heal more quickly and restore sexual function to normal levels through the generation of energy, distributing nutrients, and assisting in cell regeneration.

NanoVi

By boosting the immune system, NanoVi assists in healing DNA and cell damage. At the same time, it also boosts vitality and delays the aging process non-invasively and without the use of any toxic chemicals. In the process, it aids in prostate and penis endothelial function restoration. Recent studies have shown that NanoVi works great when used in conjunction with shockwave therapy and EMTT therapy. A lot of men with PD have gained satisfactory results after undergoing NanoVi treatment.

Conclusion:

Peyronie’s disease is a condition that has been recognized for over 250 years. Although the etiology of the disease remains unclear, it is now widely accepted that it is caused by repetitive trauma or microtrauma to the penis. The clinical features of the disease include the formation of fibrous plaques in the tunica albuginea, which results in the abnormal curvature of the penis during an erection. The treatment of Peyronie’s disease has been subject to much debate over time, and surgical intervention was the only treatment option available in the past. However, non-surgical treatments, such as oral medications, injection therapies, penile traction devices, shockwave therapy, EMTT therapy, Tesla Chair and NanoVi have become more widely available and have been shown to be effective in many cases. Further research is needed to determine the long-term safety and effectiveness of these non-surgical treatments. 

Unfortunately, every clinic doesn’t offer modern non-invasive treatments such as shockwave therapy and EMTT therapy in order to treat PD for men. But, one clinic that is highly reputable and considered one of the best in providing these treatments, is Shockwave Clinics Ltd. It is a specialized men’s health clinic situated in London. This clinic offers excellent shockwave therapy, as well as EMTT therapy, NanoVi and Tesla Chair for the treatment of PD, ED and other sexual issues in men.